Insilico Medicine Nominates ISM5059, the Peripheral-restricted NLRP3 Inhibitor as Preclinical Candidate, for the Treatment of Multiple Inflammatory and Metabolism Indications
NLRP3 is a validated anti-inflammatory target that mediates the release of proinflammatory cytokines IL-1β and IL-18, and ISM5059 targets systemic inflammatory conditions by targeting NLRP3 and blocking the inflammatory cascade at its source. Unlike...
Widest and Highest-Grade Caesium Intercepts to Date at Vega including 28.0 m at 8.05% Cs2O and 2.2 m at 26.48% Cs2O
MONTREAL, Feb. 4, 2026 /PRNewswire/ -- February 4, 2026 – Sydney, Australia Highlights Widest and highest-grade caesium intercepts reported to date at the Vega Zone: 28.0 m at 8.05% Cs2O including 18.3 m at 11.84% Cs2O (CV25-948). 18.2 m at 7.13%...
Ageing, smoking, oral bacteria and genetic mutations linked to higher stomach cancer risk
Duke-NUS and NUHS scientists uncover a complex web of genetic, age-related and microbial factors that increase the risk of stomach cancer. Age-related blood cell mutations may trigger early changes in the stomach lining, offering new insights into...
Ascletis Announces U.S. FDA IND Clearance for 13-Week Phase II Study of Its Oral Small Molecule GLP-1, ASC30, in Participants with Diabetes
- The P hase II study for diabetes is a 13-week, randomized, double-blind, placebo-controlled and multi-center study to evaluate the efficacy, safety, and tolerability of ASC30 in participants with diabetes. Enrollment is expected to begin in the...
Gen Z Walks China: Building Cultural Bridges Through Youth Exchange
SHIJIAZHUANG, China, Dec. 26, 2025 /PRNewswire/ -- A News Report from Great Wall New Media: In 2025, many middle school teachers and students from several states across the United States traveled to China, driven by curiosity and anticipation about...
Mysteries of migration
BEIJING, Dec. 11, 2025 /PRNewswire/ -- A report from China Daily Visitors to the ongoing exhibition Origin and Expansions: The Austronesians and Maritime Civilization at the Chongqing China Three Gorges Museum watch artifacts on display. In the 17th...
Jiande Showcases Integrated Culture, Tourism and Sports Experiences to International Students
Light Adventure Activities Highlight the City's New Appeal to Young Global Visitors JIANDE, China, Dec. 9, 2025 /PRNewswire/ -- From December 6 to 7, 2025, the "Jiande Light Adventure Sports, Trendy New Experience" cultural tourism promotion was...
International Communication Center of Guizhou Radio and Television Station: Preserving the Classics and Keeping Culture Alive
GUIYANG, China, Nov. 28, 2025 /PRNewswire/ -- During the the World Anti-Fascist War, invaders attempted to seize the Wenlan Pavillion copy of the Si Ku Quan Shu, or Complete Library in the Four Branches of Literature. To keep this monumental...
Nation's green tech in mining highlighted
BEIJING, Oct. 24, 2025 /PRNewswire/ -- A report from China Daily Global Mining Industry In Accelerated Transformation By China Daily Nearly 450 billion yuan ($63 billion) has been invested in mineral exploration and 150 new mineral deposits have...
Lethal mutations in pregnancy loss
REYKJAVIK, Iceland, May 21, 2025 /PRNewswire/ -- In a study published in Nature today "Sequence diversity lost in early pregnancy," scientists from deCODE genetics, a subsidiary of Amgen, estimate that around one in 136 pregnancies are lost due to...